Statistical Programmer Interview Questions & Answers
40 questions for Statistical Programmer interviews — 7 easy, 29 medium, 4 hard.
About the Statistical Programmer role
A Statistical Programmer writes validated R code to produce datasets, tables, listings and figures for clinical trials and regulated research. They follow standards such as CDISC SDTM and ADaM, document every step and work with biostatisticians on analysis plans. Pharma companies and clinical research organizations in Bengaluru, Hyderabad and Mumbai increasingly use R alongside SAS for submissions. Attention to detail and documentation discipline matter more than speed here.
How do you split one column into several, or combine columns into one?
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How do you create a column with multiple conditions in dplyr?
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Why did you choose to learn R?
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Show different ways to index vectors and data frames in R.
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What is the difference between Quarto and R Markdown?
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How do you generate the same report for each of 20 regions automatically?
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Code reviews show inconsistent R code style across the team. How would you standardise it?
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How do you perform a t-test in R?
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You ran an A/B test on a checkout page: 4.1 percent conversion versus 4.6 percent. How do you decide if the difference is real?
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Where do you see yourself in three years in an R or analytics career?
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How do you write unit tests for an R function?
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What is the difference between %>% and |> in R?
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What are the main dplyr verbs?
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Explain reactivity in Shiny.
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What is the difference between reactive(), observe() and observeEvent() in Shiny?
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What are semi_join() and anti_join() used for?
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How do you connect R to a SQL database and run queries?
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What is the structure of an R package?
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How do you build a logistic regression model for churn in R?
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Why is ungroup() important in dplyr?
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Explain the d, p, q and r functions for probability distributions in R.
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Your dplyr pipeline is too slow on a 50 million row dataset. What are your options?
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How do you check whether data is normally distributed in R?
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Tell me about feedback you received in a code review and what you changed.
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Your data is heavily skewed and the sample is small. Can you still use a t-test?
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How do you compare means across more than two groups in R?
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How do you reshape data between wide and long formats in R?
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Tell me about a dashboard or app you built in R.
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You notice database passwords hardcoded in a shared R script. What do you do?
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What is Shiny and how is a Shiny app structured?
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Salary data has a few extreme values that distort averages. How do you handle them?
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What is plumber in R?
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An R script must run every morning at 7 AM and email a report. How do you schedule it?
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How do you add logging to a production R script?
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What is the difference between Pearson and Spearman correlation?
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You need month-over-month sales growth for each product. How do you calculate it in R?
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Explain Type I and Type II errors.
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What is bootstrapping and when would you use it?
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How would you impute missing values differently for each group?
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Frequently asked questions
What does a Statistical Programmer do?
A Statistical Programmer writes validated R code to produce datasets, tables, listings and figures for clinical trials and regulated research. They follow standards such as CDISC SDTM and ADaM, document every step and work with biostatisticians on analysis plans. Pharma companies and clinical research organizations in Bengaluru, Hyderabad and Mumbai increasingly use R alongside SAS for submissions. Attention to detail and documentation discipline matter more than speed here.
Which skills are tested in a Statistical Programmer interview?
Expect questions on Clinical data standards, Tables and listings, Hypothesis testing, Code validation, R Markdown. Most rounds also ask you to explain a project and solve one practical problem live.
How do I prepare for a Statistical Programmer interview?
Revise Statistics and Hypothesis Testing, Data Wrangling with dplyr and tidyr, Reports, Shiny and Production R first using the topic sheets, practise the questions on this page aloud, then do one full mock interview to practise timing.